How do I know what I want to keep? For example, "HKCU\Software\One System Care sounds like something important. Do I need to delete these things if I want to clear my PC of malware?

Re: Adwcleaner wants to delete many items in my Registry

Hello can you post us the entire log file ?

You can find it in C:/AdwCleaner/AdwCleaner[SX].txt where X is a number.